Crohn's Disease London

Causes of Chrohn's Disease and ulcerative colitis, London

At present it is not known what causes these conditions. CD and UC are similar but are most likely to be two different conditions with different causes. Both have a genetic (familial) tendency with 1 in 5 patients having a relative affected by one of other condition. This genetic tendency may lead to a change in setting of the immune system in the intestine leading to an over-reaction to bacteria or dietary components passing through the gut which then leads to inflammation in the gut lining. Other factors contribute or help to trigger the problem and include smoking, infections and psychological stress. Smoking is interesting in that whilst it clearly worsens CD, it appears to protect against UC. Some drugs may also trigger the inflammation, particularly anti-inflammatory drugs used for arthritis (NSAID’s).

How is IBD diagnosed?

The most frequent test to diagnose IBD is a colonoscopy in which a flexible camera is used to examine the large intestine and last part of the small intestine, usually under moderate sedation. Other tests are used to examine other parts of the intestine depending on the symptoms and include upper GI endoscopy, barium studies, CT and MRI scans and wireless capsule endoscopy (pill camera). Blood tests are used to show levels of inflammation and to monitor the effects of treatment.

How do I get treatment?

To get further information or treatment, please contact one of our consultants at The London Bridge Digestion centre, on:

tel: +44 (0) 20 7403 3814